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Oxymorphone is sold under the brand name Opana ER. It is a medicine used for the treatment of severe and chronic pain. The generic name of Opana ER is Oxymorphone Hydrochloride Extended-Release.
It was developed by a team of scientists in Germany around 1914. It was first patented in 1955 and then approved to be used for medicinal use in 1959.
Oxymorphone can be consumed in three types:
Opana ER (Oxymorphone extended-release tablets) is used to treat patients suffering from chronic pains. It helps to get rid of severe ongoing chronic pains.
These medicines are only recommended for patients who have been using a regular regimen of high-dose opioids over an extended period.
One should always consult with the healthcare specialists and read the prescription carefully before consuming Opana ER.
Opana ER extended tablets are available in different doses. For instance, 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg, and 40 mg. The composition of Hydrochloride per tablet determines the strength of the tablets.
The doctor will probably start with a low dose and gradually increase the power until your pain is controlled.
Usually, extended-release Opana ER pills or tablets are taken a couple of hours before your meal on an empty stomach.
The frequency of your dose depends on the pain of your body. Usually, pills are consumed every 4 to 6 hours.
The doses always depend on your health condition and the response to the treatment. Do not increase your amount or the frequency of the medication because it may show some side effects.
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Misuse of medicine can lead to addiction, overdose or even death. Opana ER taken during pregnancy could affect the baby. You may see a fatal side effect if you consume it with alcohol or other substances which cause drowsiness or slow breathing.
Not everyone who is suffering from severe pain can consume Opana ER. With every benefit, there are also some drawbacks.
Do not consume Opana ER if you are allergic to it.
You should also avoid Opana Er if you have Asthma, shortness of breath, or severe liver and lungs disease.
Before using this medicine, inform your doctor about your medical history, such as
Whether it’s Opana ER or any other medicine, you should always slow down your medicine intake by decreasing your doses, and gradually a point will come when you can stop consuming Opana ER without any withdrawal side effects.
You might see some side effects if you immediately stop consuming Opana ER like:
Though Opana ER is consumed for pain relief, it has some common side effects that you need to know!
To avoid constipation, eat diet fibre, drink plenty of water, and work out. If you feel dizzy, then slowly wake up after sleeping or slowly get up after sitting.
Other than these, some of the adverse side effects that are seen are:
In some instances, you should contact your doctor immediately or your nearest health care centres.
Opana ER is highly addictive and can lead to overdose. But how do you figure out whether you are overdosing or not? There are some symptoms that you’re going to face with the overdose of Opana ER.
The symptoms are:
Well, you may also find some other severe issues. To decrease the overdose effects, your doctor may prescribe other medicines like naloxone (Narcan) that can reverse the overdose.
In severe cases, contact the healthcare centre or specialist for immediate help.
Opana ER contains oxymorphone which is a semi-synthetic opioid analgesic. One can purchase the medicine in the form of tablets.
The tablets contain some of the inactive ingredients like:
In addition to that, the medicines are available with different power of doses with different compositions and are used according to the severity of the patient.
Though Opana ER has a high success rate, not everyone could consume it due to its side effects. Hence, there are some alternatives that a person could be prescribed by their doctor considering their health condition.
Tramadol: It is a powerful pain-relief medicine that works in treating both nerve-related and general pain. Major side effects such as nausea and sedation can be seen during the consumption of this medicine.
It is basically prescribed for back pain, body pain, and chronic pain. Its drug class is Narcotic analgesics
Gabapentin: It is a pain-relief medicine that works in treating partial-onset seizures and nerve pain. Major side effects such as dizziness or drowsiness can be seen during the consumption of this medicine.
It is basically prescribed for Postherpetic Neuralgia, Epilepsy. Its drug class is Gamma-aminobutyric acid analogs.
One more cost-effective alternative to Opana ER is Hydromorphone. It is sold under the brand name Dilaudid. Unlike Opana ER which is taken in an empty stomach before a meal, hydromorphone can be consumed without any regard to the meal. Both medicines show similar side effects.
Keep the medicine at room temperature, free of moisture and light. Don’t store it in the bathroom and keep it away from pets and children.
Be sure to dispose of this medicine once it has expired or is not needed anymore. But do not flush the medicine in the toilet or pour them down in the drains unless you are instructed to do this.
For more information, consult with your doctor or the local waste disposal business.
If you’re taking this medication regularly and you have missed a dose, make sure to take it immediately when you remember. If it’s close to the time for the next dose, you can skip any missed dose. The next dose should be taken at the same time as usual. Don’t double the dose to get caught up.
Don’t share the medicine with anyone else. This medication was given to treat your current health condition only. Don’t take it to treat another issue unless your doctor has instructed you to do this. An alternative medication may be required in this situation.
Opana as a chronic pain killer has overtaken Oxycontin. It is two times more powerful and useful than OxyContin. According to an IMS Health report, Oxymorphone has drastically increased from 268,000 to 1 million in just three years i.e. from 2007 to 2010.
The generic name of Opana ER is Oxymorphone. It is used for the treatment of medium to severe pain. Oxymorphone comes in three forms (immediate and extended-release tablet and injection).
Immediate-release tablets come in 5 mg and 10mg for faster relief. The doses are generally 5 to 20 mg every 4 to 6 hours. These medicines’ storage temperatures are 15 degrees celsius to 30 degrees celsius at room temperature.
In 2006 Opana ER was first approved to cure severe pain. Right now the medicine is marketed by Endo Pharmaceuticals.
In 2011 a new formulation of the original product was approved. It was made with psychological properties with an intent to resist the physical and chemical manipulation for abuse by injecting and snorting. Later the reformulation was disapproved by the FDA as it was against the agency standard.
In 2012, Endo again reformulated the original formula of Opana ER and brought a new version due to safety reasons but the petition was again denied by FDA as the benefits of reformulated Opana ER no longer exceed its risks.
Finally In 2017 Endo with the guidelines of the FDA announced that it has removed the reformulation version from the market.
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Depends on person to person. Dizziness is one of the common side effects of Opana Er. Always take precautions to cut down the side effects. Exercises and drinking lots of water can help you to get over some of the common side effects.
When the patient is kept on G-glycoprotein and the lever of morphine is gradually low. In such cases, Opana ER can be replaced with morphine having ADF properties like Arymo ER, Morphabond, and Embed.
If the patient has previously been treated with morphine and has tolerated it then it is a good option. In certain cases, morphine won’t be a good substitute as it can lead to neurotoxicity and later overdose of opioids can be found.
Ans. Opana comes in white or faded white color. It is completely soluble in water but has a lower solubility in alcohol and ether. The chemical formulae of Oxymorphone hydrochloride are 4, 5α -epoxy-3, 14-dihydroxy-17-methylmorphinan-6-one hydrochloride.